Protein cornichon homolog 2 (CNIH2) (NM_182553) Human Mass Spec Standard

Specifications

Product Data
Description	CNIH2 MS Standard C13 and N15-labeled recombinant protein (NP_872359)
Species	Human
Expression Host	HEK293
Expression cDNA Clone or AA Sequence	RC215357
Predicted MW	18.8 kDa
Protein Sequence	Sequence Link (showhide) >RC215357 representing NM_182553 Red=Cloning site Green=Tags(s) MAFTFAAFCYMLTLVLCASLIFFVIWHIIAFDELRTDFKNPIDQGNPARARERLKNIERICCLLRKLVVP EYSIHGLFCLMFLCAAEWVTLGLNIPLLFYHLWRYFHRPADGSEVMYDAVSIMNADILNYCQKESWCKLA FYLLSFFYYLYSMVYTLVSF TRTRPLEQKLISEEDLAANDILDYKDDDDKV
Tag	C-Myc/DDK
Purity	> 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration	>0.05 µg/µL as determined by microplate BCA method
Labeling Method	Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer	25 mM Tris-HCl, 100 mM glycine, pH 7.3
Reference Data
RefSeq	NP_872359
RefSeq Size	1399
RefSeq ORF	480
Synonyms	CNIH-2; Cnil
Locus ID	254263
Cytogenetics	11q13.2
Summary	The protein encoded by this gene is an auxiliary subunit of the ionotropic glutamate receptor of the AMPA subtype. AMPA receptors mediate fast synaptic neurotransmission in the central nervous system. This protein has been reported to interact with the Type I AMPA receptor regulatory protein isoform gamma-8 to control assembly of hippocampal AMPA receptor complexes, thereby modulating receptor gating and pharmacology. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2012]
Protein Families	Transmembrane

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