PRX (NM_020956) Human Mass Spec Standard

Specifications

Product Data
Description	PRX MS Standard C13 and N15-labeled recombinant protein (NP_066007)
Species	Human
Expression Host	HEK293
Expression cDNA Clone or AA Sequence	RC216161
Predicted MW	15.8 kDa
Protein Sequence	Sequence Link (showhide) >RC216161 representing NM_020956 Red=Cloning site Green=Tags(s) MEARSRSAEELRRAELVEIIVETEAQTGVSGINVAGGGKEGIFVRELREDSPAARSLSLQEGDQLLSARV FFENFKYEDALRLLQCAEPYKVSFCLKRTVPTGDLALRPGTVSGYEIKGPRAKVAKL TRTRPLEQKLISEEDLAANDILDYKDDDDKV
Tag	C-Myc/DDK
Purity	> 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration	>0.05 µg/µL as determined by microplate BCA method
Labeling Method	Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer	25 mM Tris-HCl, 100 mM glycine, pH 7.3
Reference Data
RefSeq	NP_066007
RefSeq Size	5502
RefSeq ORF	383
Synonyms	CMT4F
Locus ID	57716
Cytogenetics	19q13.2
Summary	This gene encodes a protein involved in peripheral nerve myelin upkeep. The encoded protein contains 2 PDZ domains which were named after PSD95 (post synaptic density protein), DlgA (Drosophila disc large tumor suppressor), and ZO1 (a mammalian tight junction protein). Two alternatively spliced transcript variants have been described for this gene which encode different protein isoforms and which are targeted differently in the Schwann cell. Mutations in this gene cause Charcot-Marie-Tooth neuoropathy, type 4F and Dejerine-Sottas neuropathy. [provided by RefSeq, Jul 2008]
Protein Families	Druggable Genome

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