AFMID (NM_001010982) Human Mass Spec Standard

Specifications

Product Data
Description	AFMID MS Standard C13 and N15-labeled recombinant protein (NP_001010982)
Species	Human
Expression Host	HEK293
Expression cDNA Clone or AA Sequence	RC217126
Predicted MW	33.8 kDa
Protein Sequence	Sequence Link (showhide) >RC217126 representing NM_001010982 Red=Cloning site Green=Tags(s) MMDVSGVGFPSKVPWKKMSAEELENQYCPSRWVVRLGAEEALRTYSQIGIEATTRARATRKSLLHVPYGD GEGEKVDIYFPDESSEALPFFLFFHGGYWQSGSKDESAFMVHPLTAQGVAVVIVAYGIAPKGTLDHMVDQ VTRSVAFVQKRYPSNKGIYLCGHSAGAHLAAMMLLADWTKHGVTPNLRGFFLVSGVFDLEPIVYTSQNVA LQLTLEDAQRNSPQLKVAQAQPVDPTCRVLVVVGQFDSPEFHRQSWEFYQTLCQGEWKASFEELHDVDHF EIVENLTQKDNVLTQIILKTIFQ TRTRPLEQKLISEEDLAANDILDYKDDDDKV
Tag	C-Myc/DDK
Purity	> 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration	>0.05 µg/µL as determined by microplate BCA method
Labeling Method	Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer	25 mM Tris-HCl, 100 mM glycine, pH 7.3
Reference Data
RefSeq	NP_001010982
RefSeq Size	1820
RefSeq ORF	909
Synonyms	FKF; KF; KFA
Locus ID	125061
Cytogenetics	17q25.3
Summary	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L-kynurenine, the second step in the kynurenine pathway of tryptophan degradation. Kynurenine may be further oxidized to nicotinic acid, NAD(H) and NADP(H). Required for elimination of toxic metabolites.[UniProtKB/Swiss-Prot Function]
Protein Pathways	Glyoxylate and dicarboxylate metabolism, Metabolic pathways, Tryptophan metabolism

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