G0 Protein alpha (GNAO1) (NM_020988) Human Mass Spec Standard

Specifications

Product Data
Description	GNAO1 MS Standard C13 and N15-labeled recombinant protein (NP_066268)
Species	Human
Expression Host	HEK293
Expression cDNA Clone or AA Sequence	RC217958
Predicted MW	40.1 kDa
Protein Sequence	Sequence Link (showhide) >RC217958 representing NM_020988 Red=Cloning site Green=Tags(s) MGCTLSAEERAALERSKAIEKNLKEDGISAAKDVKLLLLGAGESGKSTIVKQMKIIHEDGFSGEDVKQYK PVVYSNTIQSLAAIVRAMDTLGIEYGDKERKADAKMVCDVVSRMEDTEPFSAELLSAMMRLWGDSGIQEC FNRSREYQLNDSAKYYLDSLDRIGAADYQPTEQDILRTRVKTTGIVETHFTFKNLHFRLFDVGGQRSERK KWIHCFEDVTAIIFCVALSGYDQVLHEDETTNRMHESLMLFDSICNNKFFIDTSIILFLNKKDLFGEKIK KSPLTICFPEYTGPNTYEDAAAYIQAQFESKNRSPNKEIYCHMTCATDTNNIQVVFDAVTDIIIANNLRG CGLY TRTRPLEQKLISEEDLAANDILDYKDDDDKV
Tag	C-Myc/DDK
Purity	> 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration	>0.05 µg/µL as determined by microplate BCA method
Labeling Method	Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer	25 mM Tris-HCl, 100 mM glycine, pH 7.3
Reference Data
RefSeq	NP_066268
RefSeq Size	3332
RefSeq ORF	1062
Synonyms	DEE17; EIEE17; G-ALPHA-o; GNAO; HLA-DQB1; NEDIM
Locus ID	2775
Cytogenetics	16q13
Summary	The protein encoded by this gene represents the alpha subunit of the Go heterotrimeric G-protein signal-transducing complex. Defects in this gene are a cause of early-onset epileptic encephalopathy. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2015]
Protein Families	Druggable Genome
Protein Pathways	Long-term depression, Melanogenesis

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