Secretin (SCT) (NM_021920) Human Mass Spec Standard

Specifications

Product Data
Description	SCT MS Standard C13 and N15-labeled recombinant protein (NP_068739)
Species	Human
Expression Host	HEK293
Expression cDNA Clone or AA Sequence	RC218129
Predicted MW	12.8 kDa
Protein Sequence	Sequence Link (showhide) >RC218129 representing NM_021920 Red=Cloning site Green=Tags(s) MAPRPLLLLLLLLGGSAARPAPPRARRHSDGTFTSELSRLREGARLQRLLQGLVGKRSEQDAENSMAWTR LSAGLLCPSGSNMPILQAWMPLDGTWSPWLPPGPMVSEPAGAAAEGTLRPR TRTRPLEQKLISEEDLAANDILDYKDDDDKV
Tag	C-Myc/DDK
Purity	> 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration	>0.05 µg/µL as determined by microplate BCA method
Labeling Method	Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer	25 mM Tris-HCl, 100 mM glycine, pH 7.3
Reference Data
RefSeq	NP_068739
RefSeq Size	514
RefSeq ORF	363
Locus ID	6343
Cytogenetics	11p15.5
Summary	This gene encodes a member of the glucagon family of peptides. The encoded preproprotein is secreted by endocrine S cells in the proximal small intestinal mucosa as a prohormone, then proteolytically processed to generate the mature peptide hormone. The release of this active peptide hormone is stimulated by either fatty acids or acidic pH in the duodenum. This hormone stimulates the secretion of bile and bicarbonate in the duodenum, pancreatic and biliary ducts. [provided by RefSeq, Feb 2016]
Protein Families	Druggable Genome, Secreted Protein

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