NAGPA (NM_016256) Human Mass Spec Standard

CAT#: PH318271

NAGPA MS Standard C13 and N15-labeled recombinant protein (NP_057340)



  View other "NAGPA" proteins (3)

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CNY 19,520.00


货期*
4周

规格
    • 10 ug

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Specifications

Product Data
Description NAGPA MS Standard C13 and N15-labeled recombinant protein (NP_057340)
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence RC218271
Predicted MW 56.11 kDa
Protein Sequence
Tag C-Myc/DDK
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration >0.05 µg/µL as determined by microplate BCA method
Labeling Method Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer 25 mM Tris-HCl, 100 mM glycine, pH 7.3
Reference Data
RefSeq NP_057340
RefSeq Size 2219
RefSeq ORF 1545
Synonyms APAA; UCE
Locus ID 51172
Cytogenetics 16p13.3
Summary Hydrolases are transported to lysosomes after binding to mannose 6-phosphate receptors in the trans-Golgi network. This gene encodes the enzyme that catalyzes the second step in the formation of the mannose 6-phosphate recognition marker on lysosomal hydrolases. Commonly known as 'uncovering enzyme' or UCE, this enzyme removes N-acetyl-D-glucosamine (GlcNAc) residues from GlcNAc-alpha-P-mannose moieties and thereby produces the recognition marker. The encoded preproprotein is proteolytically processed by furin to generate the mature enzyme, a homotetramer of two disulfide-linked homodimers. Mutations in this gene are associated with developmental stuttering in human patients. [provided by RefSeq, Oct 2015]
Protein Families Transmembrane
Protein Pathways Lysosome
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