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ABAT (NM_020686) Human Mass Spec Standard
CAT＃: PH318980
ABAT MS Standard C13 and N15-labeled recombinant protein (NP_065737)
View other "ABAT" proteins (11)
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CNY 19,520.00
Product images
CNY 3,080.00
CNY 1,999.00
CNY 2,700.00
Specifications
| Product Data | |
| Description | ABAT MS Standard C13 and N15-labeled recombinant protein (NP_065737) |
| Species | Human |
| Expression Host | HEK293 |
| Expression cDNA Clone or AA Sequence | RC218980 |
| Predicted MW | 56.5 kDa |
| Protein Sequence |
>RC218980 protein sequence
Red=Cloning site Green=Tags(s) MASMLLAQRLACSFQHSYRLLVPGSRHISQAAAKVDVEFDYDGPLMKTEVPGPRSRELMKQLNIIQNAEA VHFFCNYEESRGNYLVDVDGNRMLDLYSQISSVPIGYSHPALLKLIQQPQNASMFVNRPALGILPPENFV EKLRQSLLSVAPKGMSQLITMACGSCSNENALKTIFMWYRSKERGQRGFSQEELETCMINQAPGCPDYSI LSFMGAFHGRTMGCLATTHSKAIHKIDIPSFDWPIAPFPRLKYPLEEFVKENQQEEARCLEEVEDLIVKY RKKKKTVAGIIVEPIQSEGGDNHASDDFFRKLRDIARKHGCAFLVDEVQTGGGCTGKFWAHEHWGLDDPA DVMTFSKKMMTGGFFHKEEFRPNAPYRIFNTWLGDPSKNLLLAEVINIIKREDLLNNAAHAGKALLTGLL DLQARYPQFISRVRGRGTFCSFDTPDDSIRNKLILIARNKGVVLGGCGDKSIRFRPTLVFRDHHAHLFLN IFSDILADFK TRTRPLEQKLISEEDLAANDILDYKDDDDKV |
| Tag | C-Myc/DDK |
| Purity | > 80% as determined by SDS-PAGE and Coomassie blue staining |
| Concentration | >0.05 µg/µL as determined by microplate BCA method |
| Labeling Method | Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine |
| Buffer | 25 mM Tris-HCl, 100 mM glycine, pH 7.3 |
| Reference Data | |
| RefSeq | NP_065737 |
| RefSeq Size | 4814 |
| RefSeq ORF | 1500 |
| Synonyms | GABA-AT; GABAT; NPD009 |
| Locus ID | 18 |
| Cytogenetics | 16p13.2 |
| Summary | 4-aminobutyrate aminotransferase (ABAT) is responsible for catabolism of gamma-aminobutyric acid (GABA), an important, mostly inhibitory neurotransmitter in the central nervous system, into succinic semialdehyde. The active enzyme is a homodimer of 50-kD subunits complexed to pyridoxal-5-phosphate. The protein sequence is over 95% similar to the pig protein. GABA is estimated to be present in nearly one-third of human synapses. ABAT in liver and brain is controlled by 2 codominant alleles with a frequency in a Caucasian population of 0.56 and 0.44. The ABAT deficiency phenotype includes psychomotor retardation, hypotonia, hyperreflexia, lethargy, refractory seizures, and EEG abnormalities. Multiple alternatively spliced transcript variants encoding the same protein isoform have been found for this gene. [provided by RefSeq, Jul 2008] |
| Protein Families | Druggable Genome |
| Protein Pathways | Alanine, aspartate and glutamate metabolism, beta-Alanine metabolism, Butanoate metabolism, Metabolic pathways, Propanoate metabolism, Valine, leucine and isoleucine degradation |
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| 蛋白相关资源 |
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| LC400218 | ABAT HEK293T cell transient overexpression lysate (as WB positive control) |
CNY 900.00 |
|
| LC412383 | ABAT HEK293T cell transient overexpression lysate (as WB positive control) |
CNY 900.00 |
|
| LC426789 | ABAT HEK293T cell transient overexpression lysate (as WB positive control) |
CNY 900.00 |
|
| LY400218 | Transient overexpression lysate of 4-aminobutyrate aminotransferase (ABAT), nuclear gene encoding mitochondrial protein, transcript variant 2 |
CNY 3,080.00 |
|
| LY412383 | Transient overexpression lysate of 4-aminobutyrate aminotransferase (ABAT), nuclear gene encoding mitochondrial protein, transcript variant 1 |
CNY 3,080.00 |
|
| LY426789 | Transient overexpression lysate of 4-aminobutyrate aminotransferase (ABAT), transcript variant 3 |
CNY 3,080.00 |
|
| PH306793 | ABAT MS Standard C13 and N15-labeled recombinant protein (NP_000654) |
CNY 19,520.00 |
|
| PH325860 | ABAT MS Standard C13 and N15-labeled recombinant protein (NP_001120920) |
CNY 19,520.00 |
|
| TP306793 | Recombinant protein of human 4-aminobutyrate aminotransferase (ABAT), nuclear gene encoding mitochondrial protein, transcript variant 2, 20 µg |
CNY 2,900.00 |
|
| TP318980 | Recombinant protein of human 4-aminobutyrate aminotransferase (ABAT), nuclear gene encoding mitochondrial protein, transcript variant 1, 20 µg |
CNY 2,900.00 |
|
| TP325860 | Recombinant protein of human 4-aminobutyrate aminotransferase (ABAT), transcript variant 3, 20 µg |
CNY 2,900.00 |
