C4BPB (NM_001017364) Human Mass Spec Standard

CAT#: PH319158

C4BPB MS Standard C13 and N15-labeled recombinant protein (NP_001017364)



  View other "C4BPB" proteins (15)

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CNY 14,250.00


货期*
5周

规格
    • 10 ug

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Transient overexpression lysate of complement component 4 binding protein, beta (C4BPB), transcript variant 1
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Specifications

Product Data
Description C4BPB MS Standard C13 and N15-labeled recombinant protein (NP_001017364)
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence RC219158
Predicted MW 28.29 kDa
Protein Sequence
Tag C-Myc/DDK
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration >0.05 µg/µL as determined by microplate BCA method
Labeling Method Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer 25 mM Tris-HCl, 100 mM glycine, pH 7.3
Reference Data
RefSeq NP_001017364
RefSeq Size 1128
RefSeq ORF 753
Synonyms C4BP
Locus ID 725
Cytogenetics 1q32.1
Summary This gene encodes a member of a superfamily of proteins composed predominantly of tandemly arrayed short consensus repeats of approximately 60 amino acids. A single, unique beta-chain encoded by this gene assembles with seven identical alpha-chains into the predominant isoform of C4b-binding protein, a multimeric protein that controls activation of the complement cascade through the classical pathway. C4b-binding protein has a regulatory role in the coagulation system also, mediated through the beta-chain binding of protein S, a vitamin K-dependent protein that serves as a cofactor of activated protein C. The genes encoding both alpha and beta chains are located adjacent to each other on human chromosome 1 in the regulator of complement activation gene cluster. Alternative splicing gives rise to multiple transcript variants. [provided by RefSeq, Jul 2008]
Protein Pathways Complement and coagulation cascades
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