WWOX (NM_016373) Human Mass Spec Standard

CAT#: PH320747

WWOX MS Standard C13 and N15-labeled recombinant protein (NP_057457)



  View other "WWOX" proteins (3)

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CNY 19,520.00


货期*
4周

规格
    • 10 ug

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经常一起买 (2)
Transient overexpression lysate of WW domain containing oxidoreductase (WWOX), transcript variant 1
    • 100 ug

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Rabbit Polyclonal WWOX Antibody
    • 100 ul

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Specifications

Product Data
Description WWOX MS Standard C13 and N15-labeled recombinant protein (NP_057457)
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence RC220747
Predicted MW 46.5 kDa
Protein Sequence
Tag C-Myc/DDK
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration >0.05 µg/µL as determined by microplate BCA method
Labeling Method Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer 25 mM Tris-HCl, 100 mM glycine, pH 7.3
Reference Data
RefSeq NP_057457
RefSeq Size 2264
RefSeq ORF 1242
Synonyms D16S432E; DEE28; EIEE28; FOR; FRA16D; HHCMA56; PRO0128; SCAR12; SDR41C1; WOX1
Locus ID 51741
Cytogenetics 16q23.1-q23.2
Summary This gene encodes a member of the short-chain dehydrogenases/reductases (SDR) protein family. This gene spans the FRA16D common chromosomal fragile site and appears to function as a tumor suppressor gene. Expression of the encoded protein is able to induce apoptosis, while defects in this gene are associated with multiple types of cancer. Disruption of this gene is also associated with autosomal recessive spinocerebellar ataxia 12. Disruption of a similar gene in mouse results in impaired steroidogenesis, additionally suggesting a metabolic function for the protein. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2014]
Protein Families Druggable Genome
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