Lipophilin B (SCGB1D2) (NM_006551) Human Mass Spec Standard

Specifications

Product Data
Description	SCGB1D2 MS Standard C13 and N15-labeled recombinant protein (NP_006542)
Species	Human
Expression Host	HEK293
Expression cDNA Clone or AA Sequence	RC220905
Predicted MW	9.9 kDa
Protein Sequence	Sequence Link (showhide) >RC220905 protein sequence Red=Cloning site Green=Tags(s) MKLSVCLLLVTLALCCYQANAEFCPALVSELLDFFFISEPLFKLSLAKFDAPPEAVAAKLGVKRCTDQMS LQKRSLIAEVLVKILKKCSV TRTRPLEQKLISEEDLAANDILDYKDDDDKV
Tag	C-Myc/DDK
Purity	> 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration	>0.05 µg/µL as determined by microplate BCA method
Labeling Method	Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer	25 mM Tris-HCl, 100 mM glycine, pH 7.3
Reference Data
RefSeq	NP_006542
RefSeq Size	454
RefSeq ORF	270
Synonyms	LIPB; LPHB; LPNB
Locus ID	10647
Cytogenetics	11q12.3
Summary	The protein encoded by this gene is a member of the lipophilin subfamily, part of the uteroglobin superfamily, and is an ortholog of prostatein, the major secretory glycoprotein of the rat ventral prostate gland. Lipophilin gene products are widely expressed in normal tissues, especially in endocrine-responsive organs. Assuming that human lipophilins are the functional counterparts of prostatein, they may be transcriptionally regulated by steroid hormones, with the ability to bind androgens, other steroids and possibly bind and concentrate estramustine, a chemotherapeutic agent widely used for prostate cancer. Although the gene has been reported to be on chromosome 10, this sequence appears to be from a cluster of genes on chromosome 11 that includes mammaglobin 2. [provided by RefSeq, Jul 2008]
Protein Families	Secreted Protein

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