BEX1 (NM_018476) Human Mass Spec Standard

Specifications

Product Data
Description	BEX1 MS Standard C13 and N15-labeled recombinant protein (NP_060946)
Species	Human
Expression Host	HEK293
Expression cDNA Clone or AA Sequence	RC220965
Predicted MW	14.9 kDa
Protein Sequence	Sequence Link (showhide) >RC220965 protein sequence Red=Cloning site Green=Tags(s) MESKEKRAVNSLSMENANQENEEKEQVANKGEPLALPLDAGEYCVPRGNRRRFRVRQPILQYRWDMMHRL GEPQARMREENMERIGEEVRQLMEKLREKQLSHSLRAVSTDPPHHDHHDEFCLMP TRTRPLEQKLISEEDLAANDILDYKDDDDKV
Tag	C-Myc/DDK
Purity	> 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration	>0.05 µg/µL as determined by microplate BCA method
Labeling Method	Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer	25 mM Tris-HCl, 100 mM glycine, pH 7.3
Reference Data
RefSeq	NP_060946
RefSeq Size	862
RefSeq ORF	375
Synonyms	BEX2; HBEX2; HGR74-h
Locus ID	55859
Cytogenetics	Xq22
Summary	Signaling adapter molecule involved in p75NTR/NGFR signaling. Plays a role in cell cycle progression and neuronal differentiation. Inhibits neuronal differentiation in response to nerve growth factor (NGF). May act as a link between the cell cycle and neurotrophic factor signaling, possibly by functioning as an upstream modulator of receptor signaling, coordinating biological responses to external signals with internal cellular states (By similarity).[UniProtKB/Swiss-Prot Function]

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