Uroguanylin (GUCA2B) (NM_007102) Human Mass Spec Standard

Specifications

Product Data
Description	GUCA2B MS Standard C13 and N15-labeled recombinant protein (NP_009033)
Species	Human
Expression Host	HEK293
Expression cDNA Clone or AA Sequence	RC221085
Predicted MW	12.1 kDa
Protein Sequence	Sequence Link (showhide) >RC221085 protein sequence Red=Cloning site Green=Tags(s) MGCRAASGLLPGVAVVLLLLLQSTQSVYIQYQGFRVQLESMKKLSDLEAQWAPSPRLQAQSLLPAVCHHP ALPQDLQPVCASQEASSIFKTLRTIANDDCELCVNVACTGCL TRTRPLEQKLISEEDLAANDILDYKDDDDKV
Tag	C-Myc/DDK
Purity	> 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration	>0.05 µg/µL as determined by microplate BCA method
Labeling Method	Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer	25 mM Tris-HCl, 100 mM glycine, pH 7.3
Reference Data
RefSeq	NP_009033
RefSeq Size	597
RefSeq ORF	336
Synonyms	GCAP-II; UGN
Locus ID	2981
Cytogenetics	1p34.2
Summary	This gene encodes a preproprotein that is proteolytically processed to generate multiple protein products, including uroguanylin, a member of the guanylin family of peptides and an endogenous ligand of the guanylate cyclase-C receptor. Binding of this peptide to its cognate receptor stimulates an increase in cyclic GMP and may regulate salt and water homeostasis in the intestine and kidneys. [provided by RefSeq, Nov 2015]
Protein Families	Druggable Genome, Secreted Protein, Transmembrane

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