ATP6V1G3 (NM_133262) Human Mass Spec Standard

CAT#: PH321453

ATP6V1G3 MS Standard C13 and N15-labeled recombinant protein (NP_573569)



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CNY 19,520.00


货期*
4周

规格
    • 10 ug

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Specifications

Product Data
Description ATP6V1G3 MS Standard C13 and N15-labeled recombinant protein (NP_573569)
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence RC221453
Predicted MW 13.9 kDa
Protein Sequence
Tag C-Myc/DDK
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration >0.05 µg/µL as determined by microplate BCA method
Labeling Method Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer 25 mM Tris-HCl, 100 mM glycine, pH 7.3
Reference Data
RefSeq NP_573569
RefSeq Size 645
RefSeq ORF 354
Synonyms ATP6G3; Vma10
Locus ID 127124
Cytogenetics 1q31.3
Summary This gene encodes a component of vacuolar ATPase (V-ATPase), a multisubunit enzyme that mediates acidification of eukaryotic intracellular organelles. V-ATPase dependent organelle acidification is necessary for such intracellular processes as protein sorting, zymogen activation, receptor-mediated endocytosis, and synaptic vesicle proton gradient generation. V-ATPase is composed of a cytosolic V1 domain and a transmembrane V0 domain. The V1 domain consists of three A and three B subunits, two G subunits plus the C, D, E, F, and H subunits. The V1 domain contains the ATP catalytic site. The V0 domain consists of five different subunits: a, c, c', c'' and d. Additional isoforms of many of the V1 and V0 subunit proteins are encoded by multiple genes or alternatively spliced transcript variants. This gene encodes one of three G subunit proteins. Transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Protein Pathways Epithelial cell signaling in Helicobacter pylori infection, Metabolic pathways, Oxidative phosphorylation, Vibrio cholerae infection
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