CARD11 (NM_032415) Human Mass Spec Standard

CAT#: PH322740

CARD11 MS Standard C13 and N15-labeled recombinant protein (NP_115791)



  View other "CARD11" proteins (3)

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CNY 14,250.00


货期*
5周

规格
    • 10 ug

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Specifications

Product Data
Description CARD11 MS Standard C13 and N15-labeled recombinant protein (NP_115791)
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence RC222740
Predicted MW 133.3 kDa
Protein Sequence
Tag C-Myc/DDK
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration >0.05 µg/µL as determined by microplate BCA method
Labeling Method Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer 25 mM Tris-HCl, 100 mM glycine, pH 7.3
Reference Data
RefSeq NP_115791
RefSeq Size 4372
RefSeq ORF 3462
Synonyms BENTA; BIMP3; CARMA1; IMD11; IMD11A; PPBL
Locus ID 84433
Cytogenetics 7p22.2
Summary The protein encoded by this gene belongs to the membrane-associated guanylate kinase (MAGUK) family, a class of proteins that functions as molecular scaffolds for the assembly of multiprotein complexes at specialized regions of the plasma membrane. This protein is also a member of the CARD protein family, which is defined by carrying a characteristic caspase-associated recruitment domain (CARD). This protein has a domain structure similar to that of CARD14 protein. The CARD domains of both proteins have been shown to specifically interact with BCL10, a protein known to function as a positive regulator of cell apoptosis and NF-kappaB activation. When expressed in cells, this protein activated NF-kappaB and induced the phosphorylation of BCL10. [provided by RefSeq, Jul 2008]
Protein Families Druggable Genome
Protein Pathways B cell receptor signaling pathway, T cell receptor signaling pathway
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