PICK1 (NM_012407) Human Mass Spec Standard

CAT#: PH322869

PICK1 MS Standard C13 and N15-labeled recombinant protein (NP_036539)



  View other "PICK1" proteins (13)

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CNY 19,520.00


货期*
4周

规格
    • 10 ug

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Transient overexpression lysate of protein interacting with PRKCA 1 (PICK1), transcript variant 3
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Specifications

Product Data
Description PICK1 MS Standard C13 and N15-labeled recombinant protein (NP_036539)
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence RC222869
Predicted MW 46.6 kDa
Protein Sequence
Tag C-Myc/DDK
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration >0.05 µg/µL as determined by microplate BCA method
Labeling Method Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer 25 mM Tris-HCl, 100 mM glycine, pH 7.3
Reference Data
RefSeq NP_036539
RefSeq Size 2224
RefSeq ORF 1245
Synonyms PICK; PRKCABP
Locus ID 9463
Cytogenetics 22q13.1
Summary The protein encoded by this gene contains a PDZ domain, through which it interacts with protein kinase C, alpha (PRKCA). This protein may function as an adaptor that binds to and organizes the subcellular localization of a variety of membrane proteins. It has been shown to interact with multiple glutamate receptor subtypes, monoamine plasma membrane transporters, as well as non-voltage gated sodium channels, and may target PRKCA to these membrane proteins and thus regulate their distribution and function. This protein has also been found to act as an anchoring protein that specifically targets PRKCA to mitochondria in a ligand-specific manner. Three transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008]
Protein Families Druggable Genome
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