ATP7B (NM_000053) Human Mass Spec Standard

CAT#: PH323635

ATP7B MS Standard C13 and N15-labeled recombinant protein (NP_000044)



  View other "ATP7B" proteins (4)

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CNY 19,520.00


货期*
4周

规格
    • 10 ug

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经常一起买 (2)
Transient overexpression lysate of ATPase, Cu++ transporting, beta polypeptide (ATP7B), transcript variant 1
    • 100 ug

CNY 4,840.00


Rabbit polyclonal ATP7B Antibody (C-term)
    • 400 ul

CNY 6,160.00

Specifications

Product Data
Description ATP7B MS Standard C13 and N15-labeled recombinant protein (NP_000044)
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence RC223635
Predicted MW 157.1 kDa
Protein Sequence
Tag C-Myc/DDK
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration >0.05 µg/µL as determined by microplate BCA method
Labeling Method Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer 25 mM Tris-HCl, 100 mM glycine, pH 7.3
Reference Data
RefSeq NP_000044
RefSeq Size 6644
RefSeq ORF 4395
Synonyms PWD; WC1; WD; WND
Locus ID 540
Cytogenetics 13q14.3
Summary This gene is a member of the P-type cation transport ATPase family and encodes a protein with several membrane-spanning domains, an ATPase consensus sequence, a hinge domain, a phosphorylation site, and at least 2 putative copper-binding sites. This protein is a monomer, and functions as a copper-transporting ATPase which exports copper out of the cells, such as the efflux of hepatic copper into the bile. Alternate transcriptional splice variants, encoding different isoforms with distinct cellular localizations, have been characterized. Mutations in this gene have been associated with Wilson disease which is characterized by copper accumulation. [provided by RefSeq, Dec 2019]
Protein Families Druggable Genome, Transmembrane
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