NACA (NM_001113202) Human Mass Spec Standard

CAT#: PH325257

NACA MS Standard C13 and N15-labeled recombinant protein (NP_001106673)



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CNY 19,520.00


货期*
4周

规格
    • 10 ug

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Specifications

Product Data
Description NACA MS Standard C13 and N15-labeled recombinant protein (NP_001106673)
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence RC225257
Predicted MW 23.4 kDa
Protein Sequence
Tag C-Myc/DDK
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration >0.05 µg/µL as determined by microplate BCA method
Labeling Method Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer 25 mM Tris-HCl, 100 mM glycine, pH 7.3
Reference Data
RefSeq NP_001106673
RefSeq ORF 645
Synonyms HSD48; NAC-alpha; NACA1; skNAC
Locus ID 4666
Cytogenetics 12q13.3
Summary This gene encodes a protein that associates with basic transcription factor 3 (BTF3) to form the nascent polypeptide-associated complex (NAC). This complex binds to nascent proteins that lack a signal peptide motif as they emerge from the ribosome, blocking interaction with the signal recognition particle (SRP) and preventing mistranslocation to the endoplasmic reticulum. This protein is an IgE autoantigen in atopic dermatitis patients. Alternative splicing results in multiple transcript variants, but the full length nature of some of these variants, including those encoding very large proteins, has not been determined. There are multiple pseudogenes of this gene on different chromosomes. [provided by RefSeq, Feb 2016]
Protein Families Druggable Genome, Transcription Factors
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