SETBP1 (NM_001130110) Human Mass Spec Standard

Specifications

Product Data
Description	SETBP1 MS Standard C13 and N15-labeled recombinant protein (NP_001123582)
Species	Human
Expression Host	HEK293
Expression cDNA Clone or AA Sequence	RC225305
Predicted MW	26.2 kDa
Protein Sequence	Sequence Link (showhide) >RC225305 representing NM_001130110 Red=Cloning site Green=Tags(s) MESRETLSSSRQRGGESDFLPVSSAKPPAAPGCAGEPLLSTPGPGKGIPVGGERMEPEEEDELGSGRDVD SNSNADSEKWVAGDGLEEQEFSIKEANFTEGSLKLKIQTTKRAKKPPKNLENYICPPEIKITIKQSGDQK VSRAGKNSKATKEEERSHSKKKLLTASDLAASDLKGFQPQIKDSSKEEVWKRRGGQGIPFKKQFLSQERA MCFSCPRNPFPAKPGSLTLPFHSEPAVWAQEV TRTRPLEQKLISEEDLAANDILDYKDDDDKV
Tag	C-Myc/DDK
Purity	> 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration	>0.05 µg/µL as determined by microplate BCA method
Labeling Method	Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer	25 mM Tris-HCl, 100 mM glycine, pH 7.3
Reference Data
RefSeq	NP_001123582
RefSeq ORF	726
Synonyms	MRD29; SEB
Locus ID	26040
Cytogenetics	18q12.3
Summary	This gene encodes a protein which contains a several motifs including a ski homology region and a SET-binding region in addition to three nuclear localization signals. The encoded protein has been shown to bind the SET nuclear oncogene which is involved in DNA replication. Mutations in this gene are associated with Schinzel-Giedion midface retraction syndrome. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2011]

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