Filamin A (FLNA) (NM_001110556) Human Mass Spec Standard

CAT#: PH326488

FLNA MS Standard C13 and N15-labeled recombinant protein (NP_001104026)



  View other "Filamin A" proteins (3)

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CNY 14,250.00


货期*
5周

规格
    • 10 ug

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经常一起买 (2)
Rabbit polyclonal Filamin A (Ser2152) antibody(Phospho-specific)
    • 100 ul

CNY 3,280.00


Transient overexpression lysate of filamin A, alpha (FLNA), transcript variant 1
    • 100 ug

CNY 4,840.00

Specifications

Product Data
Description FLNA MS Standard C13 and N15-labeled recombinant protein (NP_001104026)
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence RC226488
Predicted MW 280.6 kDa
Protein Sequence
Tag C-Myc/DDK
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration >0.05 µg/µL as determined by microplate BCA method
Labeling Method Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer 25 mM Tris-HCl, 100 mM glycine, pH 7.3
Reference Data
RefSeq NP_001104026
RefSeq ORF 7941
Synonyms ABP-280; ABPX; CSBS; CVD1; FGS2; FLN; FLN-A; FLN1; FMD; MNS; NHBP; OPD; OPD1; OPD2; XLVD; XMVD
Locus ID 2316
Cytogenetics Xq28
Summary The protein encoded by this gene is an actin-binding protein that crosslinks actin filaments and links actin filaments to membrane glycoproteins. The encoded protein is involved in remodeling the cytoskeleton to effect changes in cell shape and migration. This protein interacts with integrins, transmembrane receptor complexes, and second messengers. Defects in this gene are a cause of several syndromes, including periventricular nodular heterotopias (PVNH1, PVNH4), otopalatodigital syndromes (OPD1, OPD2), frontometaphyseal dysplasia (FMD), Melnick-Needles syndrome (MNS), and X-linked congenital idiopathic intestinal pseudoobstruction (CIIPX). Two transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Mar 2009]
Protein Pathways Focal adhesion, MAPK signaling pathway
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