PKR (EIF2AK2) (NM_001135651) Human Mass Spec Standard

CAT#: PH326606

EIF2AK2 MS Standard C13 and N15-labeled recombinant protein (NP_001129123)



  View other "PKR" proteins (8)

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CNY 14,250.00


货期*
5周

规格
    • 10 ug

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Specifications

Product Data
Description EIF2AK2 MS Standard C13 and N15-labeled recombinant protein (NP_001129123)
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence RC226606
Predicted MW 62.1 kDa
Protein Sequence
Tag C-Myc/DDK
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration >0.05 µg/µL as determined by microplate BCA method
Labeling Method Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer 25 mM Tris-HCl, 100 mM glycine, pH 7.3
Reference Data
RefSeq NP_001129123
RefSeq Size 4127
RefSeq ORF 1653
Synonyms EIF2AK1; LEUDEN; PKR; PPP1R83; PRKR
Locus ID 5610
Cytogenetics 2p22.2
Summary The protein encoded by this gene is a serine/threonine protein kinase that is activated by autophosphorylation after binding to dsRNA. The activated form of the encoded protein can phosphorylate translation initiation factor EIF2S1, which in turn inhibits protein synthesis. This protein is also activated by manganese ions and heparin. Three transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Oct 2011]
Protein Families Druggable Genome, Protein Kinase, Transcription Factors
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