HBB Mutant (T87Q) Human Recombinant Protein

Specifications

Product Data
Description	Purified mutant recombinant protein of Human hemoglobin, beta (HBB)，mutation at（T87Q）
Species	Human
Expression Host	HEK293T
Expression cDNA Clone or AA Sequence	A DNA sequence from TrueORF clone, RC203258, encoding the full-length of HBB(T87Q)
Tag	Myc-DDK
Predicted MW	15.8 kDa
Concentration	>0.05 µg/µL as determined by microplate Bradford method
Purity	> 80% as determined by SDS-PAGE and Coomassie blue staining
Buffer	25 mM Tris-HCl, 100 mM glycine, pH 7.3, 10% glycerol
Note	For culture applications, please filter before use. Note that you may experience some loss of protein during the filtration process.
Storage	Store at -80°C after receiving vials.
Stability	Stable for at least 12 months from receipt of products under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
Reference Data
RefSeq	NP_000509.1
Locus ID	3043
Refseq Size	626
Cytogenetics	11p15.4
Refseq ORF	441
Synonyms	beta-globin; CD113t-C; ECYT6
Summary	The alpha (HBA) and beta (HBB) loci determine the structure of the 2 types of polypeptide chains in adult hemoglobin, Hb A. The normal adult hemoglobin tetramer consists of two alpha chains and two beta chains. Mutant beta globin causes sickle cell anemia. Absence of beta chain causes beta-zero-thalassemia. Reduced amounts of detectable beta globin causes beta-plus-thalassemia. The order of the genes in the beta-globin cluster is 5'-epsilon -- gamma-G -- gamma-A -- delta -- beta--3'. [provided by RefSeq, Jul 2008]

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