Neurofilament H (200 kD) Bovine Protein
CAT#: BA1014
Neurofilament H (200 kD) bovine protein, 0.25 mg
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CNY 10,030.00
货期*
7周
规格
Specifications
Product Data | |
Description | Neurofilament H (200 kD) bovine protein, 0.25 mg |
Species | Bovine |
Protein Source | Spinal Cord |
Predicted MW | 200 kDa |
Concentration | lot specific |
Purity | >98% (determined by SDS gelelectrophoresis) |
Buffer | Presentation State: Purified State: Lyophilized |
Reconstitution | Restore with 200 µl distilled water (final volume 250 μl). Final solution: 10mM Sodium Phosphate, pH 7.5, 2mM DTT, 6M Urea, 10mM methylammonium chloride, 1 mM EDTA. |
Preparation | Lyophilized |
Applications | Protein standard in 1D and 2D SDS gelelectrophoresis. Immunoassays. Immunization. |
Protein Description | Bovine Neurofilament 200 kDa |
Note | Isoelectric Point: pI 5.5 Suitable to rebuild protofilaments and filaments under conditions of reconstitution. |
Storage | Store at 2-8°C (lyophilized) or at -20°C (reconstituted). Avoid repeated freezing and thawing. |
Stability | Shelf life: one year from despatch. |
Reference Data | |
RefSeq | NP_066554 |
Locus ID | 4744 |
Cytogenetics | 22q12.2 |
Synonyms | NEFH,NF-H,KIAA0845, NFH, 200 kDa neurofilament protein, Neurofilament triplet H protein, (Neuronal Marker), heavy polypeptide |
Summary | Neurofilaments are type IV intermediate filament heteropolymers composed of light, medium, and heavy chains. Neurofilaments comprise the axoskeleton and functionally maintain neuronal caliber. They may also play a role in intracellular transport to axons and dendrites. This gene encodes the heavy neurofilament protein. This protein is commonly used as a biomarker of neuronal damage and susceptibility to amyotrophic lateral sclerosis (ALS) has been associated with mutations in this gene. [provided by RefSeq, Oct 2008] |
Protein Families | Protein standard in 1D and 2D SDS gelelectrophoresis. Immunoassays. Immunization. |
Protein Pathways | Amyotrophic lateral sclerosis (ALS) |
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