KMT2D Human shRNA Plasmid Kit (Locus ID 8085)

CAT#: TG311461

KMT2D - Human, 4 unique 29mer shRNA constructs in retroviral GFP vector, 5µg of each construct provided



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CNY 4,790.00


货期*
现货

规格
    • 1 kit

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Specifications

Product Data
Product Name KMT2D Human shRNA Plasmid Kit (Locus ID 8085)
Locus ID 8085
UniProt ID O14686
Synonyms AAD10; ALR; CAGL114; KABUK1; KMS; MLL2; MLL4; TNRC21
Vector pGFP-V-RS
Format Retroviral plasmids
Kit Components KMT2D - Human, 4 unique 29mer shRNA constructs in retroviral GFP vector(Gene ID = 8085). 5µg purified plasmid DNA per construct
29-mer scrambled shRNA cassette in pGFP-V-RS Vector, TR30013, included for free.
RefSeq NM_003482, NM_003482.1, NM_003482.2, NM_003482.3, BC039197, BC040663, NM_003482.4
Summary The protein encoded by this gene is a histone methyltransferase that methylates the Lys-4 position of histone H3. The encoded protein is part of a large protein complex called ASCOM, which has been shown to be a transcriptional regulator of the beta-globin and estrogen receptor genes. Mutations in this gene have been shown to be a cause of Kabuki syndrome. [provided by RefSeq, Oct 2010]
shRNA Design These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service.
Performance Guaranteed OriGene guarantees that the sequences in the shRNA expression cassettes are verified to correspond to the target gene with 100% identity. One of the four constructs at minimum are guaranteed to produce 70% or more gene expression knock-down provided a minimum transfection efficiency of 80% is achieved. Western Blot data is recommended over qPCR to evaluate the silencing effect of the shRNA constructs 72 hrs post transfection. To properly assess knockdown, the gene expression level from the included scramble control vector must be used in comparison with the target-specific shRNA transfected samples.

For non-conforming shRNA, requests for replacement product must be made within ninety (90) days from the date of delivery of the shRNA kit. To arrange for a free replacement with newly designed constructs, please contact Technical Services at techsupport@origene.com. Please provide your data indicating the transfection efficiency and measurement of gene expression knockdown compared to the scrambled shRNA control (Western Blot data preferred).
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.
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