NRF1 Human shRNA Plasmid Kit (Locus ID 4899)
CAT#: TR311098
NRF1 - Human, 4 unique 29mer shRNA constructs in retroviral untagged vector, 5µg of each construct provided
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CNY 6,790.00
货期*
2周
规格
Cited in 1 publication. |
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经常一起买 (2)
Specifications
Product Data | |
Product Name | NRF1 Human shRNA Plasmid Kit (Locus ID 4899) |
Locus ID | 4899 |
UniProt ID | Q16656 |
Synonyms | ALPHA-PAL |
Vector | pRS |
Format | Retroviral plasmids |
Kit Components | NRF1 - Human, 4 unique 29mer shRNA constructs in retroviral untagged vector(Gene ID = 4899). 5µg purified plasmid DNA per construct29-mer scrambled shRNA cassette in pRS Vector, TR30012, included for free. |
RefSeq | NM_001040110, NM_001293163, NM_001293164, NM_005011, NM_001040110.1, NM_005011.1, NM_005011.2, NM_005011.3, NM_005011.4, NM_001293164.1, NM_001293163.1, BC016925, BM449724, BM993780, NM_001293163.2, NM_001293164.2, NM_001040110.2 |
Summary | This gene encodes a protein that homodimerizes and functions as a transcription factor which activates the expression of some key metabolic genes regulating cellular growth and nuclear genes required for respiration, heme biosynthesis, and mitochondrial DNA transcription and replication. The protein has also been associated with the regulation of neurite outgrowth. Alternative splicing results in multiple transcript variants. Confusion has occurred in bibliographic databases due to the shared symbol of NRF1 for this gene and for "nuclear factor (erythroid-derived 2)-like 1" which has an official symbol of NFE2L1. [provided by RefSeq, May 2014] |
shRNA Design | These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service. |
Performance Guaranteed | OriGene guarantees that the sequences in the shRNA expression cassettes are verified to correspond to the target gene with 100% identity. One of the four constructs at minimum are guaranteed to produce 70% or more gene expression knock-down provided a minimum transfection efficiency of 80% is achieved. Western Blot data is recommended over qPCR to evaluate the silencing effect of the shRNA constructs 72 hrs post transfection. To properly assess knockdown, the gene expression level from the included scramble control vector must be used in comparison with the target-specific shRNA transfected samples. For non-conforming shRNA, requests for replacement product must be made within ninety (90) days from the date of delivery of the shRNA kit. To arrange for a free replacement with newly designed constructs, please contact Technical Services at techsupport@origene.com. Please provide your data indicating the transfection efficiency and measurement of gene expression knockdown compared to the scrambled shRNA control (Western Blot data preferred). |
Citations (1)
The use of this RNAi has been cited in the following citations: |
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Different roles of ROS and Nrf2 in Cr(VI)-induced inflammatory responses in normal and Cr(VI)-transformed cells
,Roy, RV;Pratheeshkumar, P;Son, YO;Wang, L;Hitron, JA;Divya, SP;Zhang, Z;Shi, X;,
Toxicol. Appl. Pharmacol.
,PubMed ID 27470422
[NRF1]
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