PKC delta (PRKCD) Human shRNA Plasmid Kit (Locus ID 5580)
CAT#: TR320468
PRKCD - Human, 4 unique 29mer shRNA constructs in retroviral untagged vector, 5µg of each construct provided
Need custom shRNA service?
Get a free quote
CNY 4,790.00
货期*
现货
规格
Cited in 6 publications. |
Product images
![](https://cdn.origene.com/img/defaults-img.jpg)
经常一起买 (2)
Specifications
Product Data | |
Product Name | PKC delta (PRKCD) Human shRNA Plasmid Kit (Locus ID 5580) |
Locus ID | 5580 |
UniProt ID | Q05655 |
Synonyms | ALPS3; CVID9; MAY1; nPKC-delta; PKCD |
Vector | pRS |
Format | Retroviral plasmids |
Kit Components | PRKCD - Human, 4 unique 29mer shRNA constructs in retroviral untagged vector(Gene ID = 5580). 5µg purified plasmid DNA per construct29-mer scrambled shRNA cassette in pRS Vector, TR30012, included for free. |
RefSeq | NM_001316327, NM_006254, NM_212539, NM_001354676, NM_001354678, NM_001354679, NM_001354680, NM_212539.1, NM_006254.1, NM_006254.2, NM_006254.3, BC043350, BC043350.1, BC127261, NM_006254.4 |
Summary | The protein encoded by this gene is a member of the protein kinase C family of serine- and threonine-specific protein kinases. The encoded protein is activated by diacylglycerol and is both a tumor suppressor and a positive regulator of cell cycle progression. Also, this protein can positively or negatively regulate apoptosis. Defects in this gene are a cause of autoimmune lymphoproliferative syndrome. [provided by RefSeq, Aug 2017] |
shRNA Design | These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service. |
Performance Guaranteed | OriGene guarantees that the sequences in the shRNA expression cassettes are verified to correspond to the target gene with 100% identity. One of the four constructs at minimum are guaranteed to produce 70% or more gene expression knock-down provided a minimum transfection efficiency of 80% is achieved. Western Blot data is recommended over qPCR to evaluate the silencing effect of the shRNA constructs 72 hrs post transfection. To properly assess knockdown, the gene expression level from the included scramble control vector must be used in comparison with the target-specific shRNA transfected samples. For non-conforming shRNA, requests for replacement product must be made within ninety (90) days from the date of delivery of the shRNA kit. To arrange for a free replacement with newly designed constructs, please contact Technical Services at techsupport@origene.com. Please provide your data indicating the transfection efficiency and measurement of gene expression knockdown compared to the scrambled shRNA control (Western Blot data preferred). |
Citations (6)
The use of this RNAi has been cited in the following citations: |
---|
Adenosine A1 receptor activation modulates human equilibrative nucleoside transporter 1 (hENT1) activity via PKC-mediated phosphorylation of serine-281
,Hughes, SJ;Cravetchi, X;Vilas, G;Hammond, JR;,
Cell. Signal.
,PubMed ID 25725289
[PRKCD]
|
Significance of host cell kinases in herpes simplex virus type 1 egress and lamin-associated protein disassembly from the nuclear lamina
,null,
Virology
,PubMed ID 20674954
[PRKCD]
|
Sprouty2 Interacts with Protein Kinase C? and Disrupts Phosphorylation of Protein Kinase D1 *
,null,
The Journal of Biological Chemistry
,PubMed ID 19458088
[PRKCD]
|
Sprouty2 Interacts with Protein Kinase C and Disrupts Phosphorylation of Protein Kinase D1
,Soah Yee Chow, Chye Yun Yu, and Graeme R. Guy,
J. Biol. Chem., Jul 2009; 284: 19623 - 19636
[PRKCD]
|
Connexin43 Potentiates Osteoblast Responsiveness to Fibroblast Growth Factor 2 via a Protein Kinase C-Delta/Runx2–dependent Mechanism
,Florence Lima, Corinne Niger, Carla Hebert, and Joseph P. Stains,
Mol. Biol. Cell, Jun 2009; 20: 2697 - 2708
[PRKCD]
|
PCPH/ENTPD5 Expression Enhances the Invasiveness of Human Prostate Cancer Cells by a Protein Kinase C{delta} Dependent Mechanism
,Joaquin Villar, Maria Isabel Arenas, Caitlin M Maccarthy, Maria Jose Blanquez, Oscar M Tirado, and Vicente Notario,
Cancer Res. 2007 Nov 15;67(22):10859-68
[PRKCD]
|
Documents
Product Manuals |
FAQs |
SDS |
Customer
Reviews
Loading...