SRC3 (NCOA3) Human shRNA Plasmid Kit (Locus ID 8202)
CAT#: TR320577
NCOA3 - Human, 4 unique 29mer shRNA constructs in retroviral untagged vector, 5µg of each construct provided
Need custom shRNA service?
Get a free quote
CNY 6,790.00
货期*
2周
规格
Cited in 1 publication. |
Product images
![](https://cdn.origene.com/img/defaults-img.jpg)
经常一起买 (2)
Specifications
Product Data | |
Product Name | SRC3 (NCOA3) Human shRNA Plasmid Kit (Locus ID 8202) |
Locus ID | 8202 |
UniProt ID | Q9Y6Q9 |
Synonyms | ACTR; AIB-1; AIB1; bHLHe42; CAGH16; CTG26; KAT13B; pCIP; RAC3; SRC-3; SRC3; TNRC14; TNRC16; TRAM-1 |
Vector | pRS |
Format | Retroviral plasmids |
Kit Components | NCOA3 - Human, 4 unique 29mer shRNA constructs in retroviral untagged vector(Gene ID = 8202). 5µg purified plasmid DNA per construct29-mer scrambled shRNA cassette in pRS Vector, TR30012, included for free. |
RefSeq | NM_001174087, NM_001174088, NM_006534, NM_181659, NM_181659.1, NM_181659.2, NM_006534.1, NM_006534.2, NM_006534.3, NM_001174088.1, NM_001174087.1, BC092516, BC119001, BC122547, BM692321, NM_006534.4, NM_181659.3, NM_001174087.2, NM_001174088.2 |
Summary | The protein encoded by this gene is a nuclear receptor coactivator that interacts with nuclear hormone receptors to enhance their transcriptional activator functions. The encoded protein has histone acetyltransferase activity and recruits p300/CBP-associated factor and CREB binding protein as part of a multisubunit coactivation complex. This protein is initially found in the cytoplasm but is translocated into the nucleus upon phosphorylation. Several transcript variants encoding different isoforms have been found for this gene. In addition, a polymorphic repeat region is found in the C-terminus of the encoded protein. [provided by RefSeq, Mar 2010] |
shRNA Design | These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service. |
Performance Guaranteed | OriGene guarantees that the sequences in the shRNA expression cassettes are verified to correspond to the target gene with 100% identity. One of the four constructs at minimum are guaranteed to produce 70% or more gene expression knock-down provided a minimum transfection efficiency of 80% is achieved. Western Blot data is recommended over qPCR to evaluate the silencing effect of the shRNA constructs 72 hrs post transfection. To properly assess knockdown, the gene expression level from the included scramble control vector must be used in comparison with the target-specific shRNA transfected samples. For non-conforming shRNA, requests for replacement product must be made within ninety (90) days from the date of delivery of the shRNA kit. To arrange for a free replacement with newly designed constructs, please contact Technical Services at techsupport@origene.com. Please provide your data indicating the transfection efficiency and measurement of gene expression knockdown compared to the scrambled shRNA control (Western Blot data preferred). |
Citations (1)
The use of this RNAi has been cited in the following citations: |
---|
Fc?-receptor IIa-mediated Src Signaling Pathway is Essential for the Antibody-Dependent Enhancement of Ebola Virus Infection
,Furuyama, W;Marzi, A;Carmody, AB;Maruyama, J;Kuroda, M;Miyamoto, H;Nanbo, A;Manzoor, R;Yoshida, R;Igarashi, M;Feldmann, H;Takada, A;,
PLoS Pathog
,PubMed ID 28036370
[NCOA3]
|
Documents
Product Manuals |
FAQs |
SDS |
Customer
Reviews
Loading...