Z DNA binding protein (ZBP1) Human siRNA Oligo Duplex (Locus ID 81030)
CAT#: SR312989
ZBP1 (Human) - 3 unique 27mer siRNA duplexes - 2 nmol each
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CNY 4,090.00
货期*
4周
规格
Cited in 2 publications. |
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经常一起买 (3)
Specifications
Product Data | |
Purity | HPLC purified |
Quality Control | Tested by ESI-MS |
Sequences | Available with shipment |
Stability | One year from date of shipment when stored at -20°C. |
# of transfections | Approximately 330 transfections/2nmol in 24-well plate under optimized conditions (final conc. 10 nM). |
Note | Single siRNA duplex (10nmol) can be ordered. |
Reference Data | |
RefSeq | NM_001160417, NM_001160418, NM_001160419, NM_001323966, NM_030776, NR_136660 |
Synonyms | C20orf183; DAI; DLM-1; DLM1 |
Components | ZBP1 (Human) - 3 unique 27mer siRNA duplexes - 2 nmol each (Locus ID 81030)Included - SR30004, Trilencer-27 Universal Scrambled Negative Control siRNA Duplex - 2 nmolIncluded - SR30005, RNAse free siRNA Duplex Resuspension Buffer - 2 ml |
Summary | This gene encodes a Z-DNA binding protein. The encoded protein plays a role in the innate immune response by binding to foreign DNA and inducing type-I interferon production. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Dec 2011] |
Performance Guranteed | OriGene guarantees that at least two of the three Dicer-Substrate duplexes in the kit will provide at least 70% or more knockdown of the target mRNA when used at 10 nM concentration by quantitative RT-PCR when the TYE-563 fluorescent transfection control duplex (cat# SR30002) indicates that >90% of the cells have been transfected and the HPRT positive control (cat# SR30003) provides 90% knockdown efficiency. For non-conforming siRNA, requests for replacement product must be made within ninety (90) days from the date of delivery of the siRNA kit. To arrange for a free replacement with newly designed duplexes, please contact Technical Services at techsupport@origene.com. Please provide your data indicating the transfection efficiency and measurement of gene expression knockdown compared to the scrambled siRNA control (quantitative RT-PCR data required). |
Citations (2)
The use of this RNAi has been cited in the following citations: |
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miR-222 Represses Expression of Zipcode Binding Protein-1 and Phospholipase C-γ1 in Intestinal Epithelial Cells
,Jiang, LP;Wang, SR;Chung, HK;Buddula, S;Wang, JY;Rao, JN;,
Am. J. Physiol., Cell Physiol.
,PubMed ID 30649922
[ZBP1]
|
Mitochondrial DNA damage and subsequent activation of Z-DNA binding protein 1 links oxidative stress to inflammation in epithelial cells
,Szczesny, B;Marcatti, M;Ahmad, A;Montalbano, M;Brunyánszki, A;Bibli, SI;Papapetropoulos, A;Szabo, C;,
Sci Rep
,PubMed ID 29343810
[ZBP1]
|
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