LAMP2 Human siRNA Oligo Duplex (Locus ID 3920)
CAT#: SR320822
LAMP2 (Human) - 3 unique 27mer siRNA duplexes - 2 nmol each
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SR320822 is the updated version of SR302652.
CNY 4,090.00
货期*
4周
规格
Cited in 2 publications. |
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经常一起买 (3)
Specifications
Product Data | |
Purity | HPLC purified |
Quality Control | Tested by ESI-MS |
Sequences | Available with shipment |
Stability | One year from date of shipment when stored at -20°C. |
# of transfections | Approximately 330 transfections/2nmol in 24-well plate under optimized conditions (final conc. 10 nM). |
Note | Single siRNA duplex (10nmol) can be ordered. |
Reference Data | |
RefSeq | NM_001122606, NM_002294, NM_013995 |
Synonyms | CD107b; DND; LAMP-2; LAMPB; LGP-96; LGP110 |
Components | LAMP2 (Human) - 3 unique 27mer siRNA duplexes - 2 nmol each (Locus ID 3920)Included - SR30004, Trilencer-27 Universal Scrambled Negative Control siRNA Duplex - 2 nmolIncluded - SR30005, RNAse free siRNA Duplex Resuspension Buffer - 2 ml |
Summary | The protein encoded by this gene is a member of a family of membrane glycoproteins. This glycoprotein provides selectins with carbohydrate ligands. It may play a role in tumor cell metastasis. It may also function in the protection, maintenance, and adhesion of the lysosome. Alternative splicing of this gene results in multiple transcript variants encoding distinct proteins. [provided by RefSeq, Jul 2008] |
Performance Guranteed | OriGene guarantees that at least two of the three Dicer-Substrate duplexes in the kit will provide at least 70% or more knockdown of the target mRNA when used at 10 nM concentration by quantitative RT-PCR when the TYE-563 fluorescent transfection control duplex (cat# SR30002) indicates that >90% of the cells have been transfected and the HPRT positive control (cat# SR30003) provides 90% knockdown efficiency. For non-conforming siRNA, requests for replacement product must be made within ninety (90) days from the date of delivery of the siRNA kit. To arrange for a free replacement with newly designed duplexes, please contact Technical Services at techsupport@origene.com. Please provide your data indicating the transfection efficiency and measurement of gene expression knockdown compared to the scrambled siRNA control (quantitative RT-PCR data required). |
Citations (2)
The use of this RNAi has been cited in the following citations: |
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Lysosome-associated membrane protein-2 deficiency increases the risk of reactive oxygen species-induced ferroptosis in retinal pigment epithelial cells
,Lee, JJ;Ishihara, K;Notomi, S;Efstathiou, NE;Ueta, T;Maidana, D;Chen, X;Iesato, Y;Caligiana, A;Vavvas, DG;,
Biochem. Biophys. Res. Commun.
,PubMed ID 31672277
[LAMP2]
|
Chronic acidosis in the tumour microenvironment selects for overexpression of LAMP2 in the plasma membrane
,null,
Nature Communications
,PubMed ID 26658462
[LAMP2]
|
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