Lrp6 Rat siRNA Oligo Duplex (Locus ID 312781)
CAT#: SR502468
Lrp6 (Rat) - 3 unique 27mer siRNA duplexes - 2 nmol each
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CNY 4,090.00
货期*
4周
规格
Cited in 6 publications. |
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经常一起买 (2)
Specifications
Product Data | |
Purity | HPLC purified |
Quality Control | Tested by ESI-MS |
Sequences | Available with shipment |
Stability | One year from date of shipment when stored at -20°C. |
# of transfections | Approximately 330 transfections/2nmol in 24-well plate under optimized conditions (final conc. 10 nM). |
Note | Single siRNA duplex (10nmol) can be ordered. |
Reference Data | |
RefSeq | NM_001107892 |
Components | Lrp6 (Rat) - 3 unique 27mer siRNA duplexes - 2 nmol each (Locus ID 312781)Included - SR30004, Trilencer-27 Universal Scrambled Negative Control siRNA Duplex - 2 nmolIncluded - SR30005, RNAse free siRNA Duplex Resuspension Buffer - 2 ml |
Performance Guranteed | OriGene guarantees that at least two of the three Dicer-Substrate duplexes in the kit will provide at least 70% or more knockdown of the target mRNA when used at 10 nM concentration by quantitative RT-PCR when the TYE-563 fluorescent transfection control duplex (cat# SR30002) indicates that >90% of the cells have been transfected and the HPRT positive control (cat# SR30003) provides 90% knockdown efficiency. For non-conforming siRNA, requests for replacement product must be made within ninety (90) days from the date of delivery of the siRNA kit. To arrange for a free replacement with newly designed duplexes, please contact Technical Services at techsupport@origene.com. Please provide your data indicating the transfection efficiency and measurement of gene expression knockdown compared to the scrambled siRNA control (quantitative RT-PCR data required). |
Citations (6)
The use of this RNAi has been cited in the following citations: |
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Activation of LRP6 with HLY78 Attenuates Oxidative Stress and Neuronal Apoptosis via GSK3β/Sirt1/PGC-1α Pathway after ICH
,null,
Oxidative Medicine and Cellular Longevity
,PubMed ID 35419167
[Lrp6]
|
Lrp6 Genotype affects Individual Susceptibility to Nonalcoholic Fatty Liver Disease and Silibinin Therapeutic Response via Wnt/β-catenin-Cyp2e1 Signaling
,null,
International Journal of Biological Sciences
,PubMed ID 34671210
[Lrp6]
|
HLY78 protects blood-brain barrier integrity through Wnt/β-catenin signaling pathway following subarachnoid hemorrhage in rats
,Luo, X;Li, L;Zheng, W;Gu, L;Zhang, X;Li, Y;Xie, Z;Cheng, Y;,
Brain Res. Bull.
,PubMed ID 32565130
[LRP6]
|
HLY78 Attenuates Neuronal Apoptosis via the LRP6/GSK3β/β-Catenin Signaling Pathway After Subarachnoid Hemorrhage in Rats
,Luo, X;Li, L;Xu, W;Cheng, Y;Xie, Z;,
Neurosci Bull
,PubMed ID 32562163
[LRP6]
|
The LRP6 functional mutation rs2302685 contributes to individual susceptibility to alcoholic liver injury related to the Wnt/β-catenin-TCF1-CYP2E1 signaling pathway.
,null,
Archives of toxicology
,PubMed ID 30976847
[Lrp6]
|
Sclerostin inhibition promotes TNF-dependent inflammatory joint destruction.
,null,
Science translational medicine
,PubMed ID 27089204
[Lrp6]
|
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