Clostridium difficile Toxin A Mouse Monoclonal Antibody [Clone ID: BDI517]

Specifications

Product Data
Clone Name	BDI517
Applications	ELISA
Recommend Dilution	ELISA.
Reactivity	Clostridium difficile
Host	Mouse
Clonality	Monoclonal
Immunogen	Purified C. difficile toxoid A.  Source: Ascites.
Specificity	Specific for toxin/toxoid A of Clostridium difficile. Does not cross react with C. difficile toxin B, tetanus toxoid, Pseudomonas aeruginosa and Yersinia enterocolitica.
Formulation	0.01M PBS, pH 7.2 State: Purified State: Liquid purified IgG fraction (> 90% pure) Stabilizer: None Preservative: 0.09% Sodium Azide
Concentration	lot specific
Purification	Protein A Chromatography
Conjugation	Unconjugated
Storage Condition	Upon receipt, store undiluted (in aliquots) at -20°C. Avoid repeated freezing and thawing.
Database Link	UniProt ID P16154
Background	Clostridium difficile is a gram-positive motile bacterium which is the leading cause of diarrhoea in developed countries. The incidence of disease in humans varies greatly with age, spore density and the administration of antibiotics. Toxin A (TcdA) is a large exotoxin which is an essential virulence factor for C. difficile infection. TcdA has a molecular weight of 308kD and is a glucosyltransferase, which irreversibly inactivates the Ras family of small GTPases to disrupt many important signalling pathways.
Synonyms	toxA, tcdA
Note	Centrifuge before opening to ensure complete recovery of vial contents.
Reference Data

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