Morphine Mouse Monoclonal Antibody [Clone ID: BDI263]

Specifications

Product Data
Clone Name	BDI263
Applications	ELISA, LF
Recommend Dilution	Tested in a rapid test (lateral flow) format.
Reactivity	Human
Host	Mouse
Clonality	Monoclonal
Immunogen	Morphine-BTG
Specificity	This antibody reacts with Morphine and Codeine. Cross reactivity was determined by ELISA with competition assays. Does not react with Nalorphine, Meperidine or Methadone.
Formulation	10mM Sodium Phosphate, pH 7.2 containing 0.85% (w/v) Sodium Chloride State: Purified State: Liquid purified Ig fraction Preservative: 0.05% Sodium Azide
Concentration	lot specific
Purification	Protein G Chromatography
Conjugation	Unconjugated
Storage Condition	Store undiluted at 2-8°C.
Background	Morphine is thought to produce reinforcement phenomena via stimulation of mu, delta, and kappa opioid receptors that regulate stress perception, pain control, reward behavior, and neurohormone secretion in reward-relevant brain systems. It has the highest affinity for mu, followed by delta and kappa. Rapid activation of the mu opioid receptor by morphine results in a euphoric phenotype, thus conferring the reinforcing effects of the drug. This activation is accompanied by extracellular dopamine release, which alters several events related to the cAMP signal transduction pathway. Of particular significance is that CREB seems to be modified by morphine, thereby affecting addictive behavioral phenomena, such as withdrawal symptoms.
Reference Data

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