CD88 / C5R1 Rat Monoclonal Antibody [Clone ID: 10/92]

Specifications

Product Data
Clone Name	10/92
Applications	FC
Recommend Dilution	Flow cytometry: use 10 µl of neat antibody to label 1x10e6 cells in 100 µl.
Reactivity	Mouse
Host	Rat
Clonality	Monoclonal
Immunogen	RBL-2H3 transfected cells expressing murine C5aR. Cells from immunised Lou/c rats were fused with cells of the X63-Ag8.653 myeloma cell line.
Specificity	This antibody recognises CD88.
Formulation	PBS, pH 7.4, containing 0.09% Sodium Azide and 1% Bovine Serum Albumin Label: Biotin State: Liquid purified IgG
Concentration	lot specific
Purification	Affinity chromatography on Protein G
Conjugation	Biotin
Storage Condition	Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing.
Gene Name	complement component 5a receptor 1
Database Link	Entrez Gene 12273 Mouse UniProt ID P30993
Background	CD88 is a 45kD G-protein coupled cell surface receptor, which is otherwise known as C5aR. The CD88 molecule functions as a receptor for the complement component C5a, which is a potent proinflammatory molecule and a chemoattractant for neutrophils to sites of infection. In mouse, CD88 is expressed on granulocytes, monocytes and macrophages but not on resting or stimulated lymphocytes.
Synonyms	C5a-R, C5aR, C5AR1, Complement Component 5a Receptor 1
Note	Clone 10/92 does not block the binding of the C5a to murine CD88.
Reference Data

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