FK506 Mouse Monoclonal Antibody [Clone ID: FK1]

Specifications

Product Data
Clone Name	FK1
Applications	ELISA
Recommend Dilution	ELISA.
Reactivity	Streptomyces tsukubaensis
Host	Mouse
Clonality	Monoclonal
Immunogen	FK-506-BSA conjugate. Spleen cells from immunised Balb/c mice were fused with cells of the Sp2/0 myeloma cell line.
Specificity	This antibody clone FK1 detects FK-506, a macrolide with similar but more potent immunosuppressant activity than cyclosporine.
Formulation	TRIS buffered saline, pH 8.0 State: Purified State: Liquid purified IgM fraction Preservative: 0.09% Sodium Azide
Concentration	lot specific
Conjugation	Unconjugated
Storage Condition	Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing.
Background	FK-506 is a 23-membered lactone produced by the bacteria Streptomyces tsukubaensis. FK-506 inhibits signal transduction and interleukin-2 transcription in CD4+ T helper lymphocytes, and is mainly used after allogenic organ transplantation to reduce organ rejection. Side effects of FK-506 treatment include nephrotoxicity, neurotoxicity, diabetes mellitus and hypertension.
Synonyms	Tacrolimus, FK-506
Reference Data

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