Complement C9 (C9) Mouse Monoclonal Antibody [Clone ID: 002-94.8.8]

Specifications

Product Data
Clone Name	002-94.8.8
Applications	ELISA
Recommend Dilution	ELISA.
Reactivity	Human
Host	Mouse
Clonality	Monoclonal
Immunogen	Purified human C9.
Specificity	This antibody recognises complement component 9 (C9), a 71kDa member of the complement C6/C7/C8/C9 family present in the blood serum and synthesised by the liver and monocytes.
Formulation	Borate buffered saline pH 8.2 - 8.4 containing 0.02% Sodium Azide State: Purified State: Liquid purified Ig
Concentration	lot specific
Purification	Affinity chromatography on Protein A
Conjugation	Unconjugated
Storage Condition	Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing.
Gene Name	complement component 9
Database Link	Entrez Gene 735 Human UniProt ID P02748
Background	C9 is the last component to be added during the formation of the membrane attack complex (MAC), binding the membrane associated C5b-8 complex and resulting in the circular polymerisation of 12-18 C9 molecules. This forms the hydrophilic transmembrane channel which causes cell lysis. Deficiency of C9 is associated with recurring infections by Neisseria meningitides.
Synonyms	Complement component C9, Complement 9
Reference Data

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