DcR1 (TNFRSF10C) Mouse Monoclonal Antibody [Clone ID: TRAIL-R3-02]

CAT#: AM03038FC-N

DcR1 (TNFRSF10C) mouse monoclonal antibody, clone TRAIL-R3-02, FITC

Conjugation: FITC PE



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CNY 5,000.00


货期*
5周

规格
    • 100 ug

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Specifications

Product Data
Clone Name TRAIL-R3-02
Applications FC
Recommend Dilution Flow Cytometry: 3 µg/ml.
Reactivity Human
Host Mouse
Clonality Monoclonal
Immunogen TRAIL-R3 (aa 1-280) - hIgGhc fusion protein.
Specificity The antibody TRAIL-R3-02 reacts with TRAIL-R3, a 35 kDa GPI-anchored extracellular membrane protein expressed mainly on neutrophils.
Formulation PBS containing 15 mM Sdium Azide as preservative and 0.2% (w/v) high-grade (Protease free) BSA as a stabilizing agent.
Label: FITC
State: Liquid purified IgG fraction.
Label: Fluorescein Isothiocyanate Isomer 1
Concentration lot specific
Conjugation FITC
Storage Condition Store the antibody undiluted at 2-8°C.
DO NOT FREEZE!
This product is photosensitive and should be protected from light.
Avoid prolonged exposure to light.
Gene Name tumor necrosis factor receptor superfamily member 10c
Background TRAIL-R3 (CD263, TR3, DcR1, LIT, TRID), expressed mainly on neutrophils, belongs to receptors of TRAIL, a TNF-like membrane cytotoxic protein that induces apoptosis in many tumour cells, but not in normal cells. TRAIL-R3, however, is a GPI-anchored protein that lacks cytoplasmic death domain, thus it is unable to induce apoptosis and serves as a negative regulator of apoptotic signaling by competing for binding of TRAIL with death receptor 5 (DR5).
Synonyms Decoy receptor 1, TNFRSF10C, DCR1, LIT, TRID, TRAIL receptor 3, TRAIL-R3
Reference Data
Protein Families Druggable Genome, Transmembrane
Protein Pathways Apoptosis, Cytokine-cytokine receptor interaction, Natural killer cell mediated cytotoxicity
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.
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