CD62P (SELP) Mouse Monoclonal Antibody [Clone ID: HI62P]

CAT#: AM03091PU-N

CD62P (SELP) mouse monoclonal antibody, clone HI62P, Aff - Purified



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CNY 3,280.00


货期*
5周

规格
    • 100 ug

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Specifications

Product Data
Clone Name HI62P
Applications FC, WB
Recommend Dilution Flow Cytometry.
Western Blotting.
Reactivity Human
Host Mouse
Clonality Monoclonal
Immunogen Human platelets.
Specificity The antibody HI62P recognizes CD62P (P-selectin), a 140 kD single chain type I transmembrane glycoprotein present in secretory α-granules in platelets, in Weibel-Palade bodies in endothelial cells and in megakaryocytes; it is relocated to the plasma membrane upon activation.
Formulation PBS, pH 7.4 with 15 mM sodium azide as preservative.
State: Aff - Purified
State: Liquid purified IgG fraction (> 95% pure by SDS-PAGE).
Concentration lot specific
Purification Protein-G affinity chromatography.
Conjugation Unconjugated
Storage Condition Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
Avoid repeated freezing and thawing.
Gene Name selectin P
Background CD62P (P-selectin) is an adhesion glycoprotein that is expressed on platelets and endothelial cells upon their activation. Interaction between CD62P and its mucin-like ligand PSGL-1 (P-selectin glycoprotein ligand-1) expressed on the microvilli of most leukocytes supports leukocyte rolling along postkapillary venules at the earliest time of inflammation. Both CD62P and PSGL-1 are extended glycoproteins that form homodimers. CD62P dimerization is probably mediated through interactions of the transmembrane domains and stabilizes leukocyte tethering and rolling, probably by increasing rebinding within a bond cluster.
Synonyms SELP, GMRP, GRMP, PADGEM, GMP-140, LECAM3
Reference Data
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.
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