Cd80 Rat Monoclonal Antibody [Clone ID: RM80]

CAT#: AM05570PU-N

Cd80 rat monoclonal antibody, clone RM80, Purified

Conjugation: Unconjugated FITC PE



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CNY 4,499.00


货期*
4周

规格
    • 100 ug

Product images

Specifications

Product Data
Clone Name RM80
Applications FC, IHC
Recommend Dilution Flow cytometry: 1/10 - 1/25, use 10 µl of the suggested working dilution to label 1x10e6 cells in 100 µl.
Immunohistochemistry on frozen sections.
Functional assays.
Reactivity Mouse
Host Rat
Clonality Monoclonal
Immunogen BCL1 cells expressing CD80
Specificity This antibody recognises CD80 (B7-1), a 60kD cell surface glycoprotein which is a member of the CD28/B7 family. In mice, CD80 is expressed on monocytes, peritoneal macrophages and dendritic cells. Expression may be significantly increased upon B lymphocytes by LPS and by IL-4.
Formulation Phosphate buffered saline, pH 7.4 containing 0.09% sodium azide.
State: Purified
State: Liquid Ig fraction
Concentration lot specific
Purification Affinity chromatography on Protein G
Conjugation Unconjugated
Storage Condition Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
Avoid repeated freezing and thawing.
Gene Name CD80 antigen
Background CD80 is a member of the Ig superfamily and serves as the ligand for two T cell molecules, CD28 and CTLA4. Interactions between CD28 and CD80 on activated B cells result in enhanced T cell activation. CD80 is rapidly induced on the surface of in vitro activated B cells, Epstein Barr Virus (EBV) transformed B cell lines, Burkitts lymphoma cell lines, freshly isolated follicular B lymphoma cells, T cells, and monocytes. It is also expressed at high levels in dendritic cells. It reacts weakly with a small proportion of non activated normal B cells and with HTLV1 infected T cells. CD80 does not react with peripheral monocytes, resting and activated normal T cells, T cell lines and T cell clones, nor with myelomonocytic cell lines.
Synonyms CD28LG, CD28LG1, LAB7, BB1, B7.1, B7-1
Reference Data
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.
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