Cd80 Rat Monoclonal Antibody [Clone ID: RM80]
CAT#: AM05570RP-N
Cd80 rat monoclonal antibody, clone RM80, PE
Conjugation: Unconjugated FITC
Need it in bulk or conjugated?
Get a free quote
CNY 6,369.00
Product images
![](https://cdn.origene.com/img/defaults-img.jpg)
Specifications
Product Data | |
Clone Name | RM80 |
Applications | FC |
Recommend Dilution | Flow Cytometry: Use 10 ul of neat antibody to label 1x10e6 cells in 100 ul. |
Reactivity | Mouse |
Host | Rat |
Clonality | Monoclonal |
Immunogen | BCL1 cells expressing CD80. |
Specificity | This antibody recognises mouse CD80 (B7-1), a 60kD cell surface glycoprotein which is a member of the CD28/B7 family. In mice, CD80 is expressed on monocytes, peritoneal macrophages and dendritic cells, and expression may be significantly increased upon B lymphocytes by LPS and by IL-4. |
Formulation | PBS, pH 7.4 containing 0.09% Sodium Azide as preservative and 1% BSA + 5% sucrose as stabilizer. Label: PE State: Lyophilized purified IgG fraction. Label: R. Phycoerythrin (RPE) |
Reconstitution Method | Reconstitute with 1.0 ml distilled water. |
Concentration | lot specific |
Purification | Affinity Chromatography on Protein G. |
Conjugation | PE |
Storage Condition | Store the antibody undiluted at 2-8°C. DO NOT FREEZE! This product is photosensitive and should be protected from light. Should this product contain a precipitate we recommend microcentrifugation before use. |
Gene Name | CD80 antigen |
Database Link | |
Background | CD80 is a member of the Ig superfamily and serves as the ligand for two T cell molecules, CD28 and CTLA4. Interactions between CD28 and CD80 on activated B cells result in enhanced T cell activation. CD80 is rapidly induced on the surface of in vitro activated B cells, Epstein Barr Virus (EBV) transformed B cell lines, Burkitts lymphoma cell lines, freshly isolated follicular B lymphoma cells, T cells, and monocytes. It is also expressed at high levels in dendritic cells. It reacts weakly with a small proportion of non activated normal B cells and with HTLV1 infected T cells. CD80 does not react with peripheral monocytes, resting and activated normal T cells, T cell lines and T cell clones, nor with myelomonocytic cell lines. |
Synonyms | CD28LG, CD28LG1, LAB7, BB1, B7.1, B7-1 |
Reference Data |
Documents
Product Manuals |
FAQs |
SDS |
Resources
抗体相关资料 |