SIRPG Mouse Monoclonal Antibody [Clone ID: OX119]

Specifications

Product Data
Clone Name	OX119
Applications	FC
Recommend Dilution	Flow Cytometry: 1/10.
Reactivity	Human
Host	Mouse
Clonality	Monoclonal
Immunogen	Purified recombinant SIRPgamma.CD4.
Specificity	This antibody recognises SIRP gamma, a 55kD signal regulatory protein which is a member of the immunoglobulin gene superfamily.
Formulation	Phosphate buffered saline pH7.4 containing 0.09% Sodium Azide (NaN3) and 1% Bovine Serum Albumin Label: PE State: Lyophilised purified IgG Label: R. Phycoerythrin (RPE)
Reconstitution Method	Reconstitute with 1.0ml distilled water
Concentration	lot specific
Purification	Affinity chromatography on Protein G
Conjugation	PE
Storage Condition	Prior to and following reconstitution store the antibody at 2-8°C. DO NOT FREEZE! This product is photosensitive and should be protected from light.
Gene Name	signal regulatory protein gamma
Database Link	Entrez Gene 55423 Human UniProt ID Q9P1W8
Background	SIRP gamma, also known as CD172g, is expressed on most T lymphocytes and a subset of B-cells but is absent on myeloid cells. CD172g has a truncated cytoplasmic tail, which is similar to SIRP beta, but unlike SIRP beta CD172g does not require DAP12 for expression at the cell surface. CD172g, like SIRP alpha, binds to CD47 inducing apoptosis. It is also involved in the negative regulation of receptor tyrosine kinase-coupled signalling.
Synonyms	SIRP-beta-2, SIRP-b2, SIRPB2, SIRP gamma
Reference Data

*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.