hspX (16 kDa Ag) Mouse Monoclonal Antibody [Clone ID: 5175]
CAT#: AM05915PU-N
hspX (16 kDa Ag) mouse monoclonal antibody, clone 5175, Purified
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CNY 8,745.00
货期*
4周
规格
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Specifications
Product Data | |
Clone Name | 5175 |
Applications | ELISA, WB |
Recommend Dilution | ELISA. Western blot. |
Reactivity | Mycobacterium tuberculosis |
Host | Mouse |
Clonality | Monoclonal |
Specificity | This antibody is specific for the 16 kDa antigen of Mycobacterium tuberculosis and Mycobacterium bovis. M. tuberculosis is the common causative agent of tuberculosis in humans. M. bovis is a closely related species which causes tuberculosis in cattle. |
Formulation | Phosphate buffered saline, 0.09% Sodium Azide (NaN3) State: Purified State: Liquid Ig fraction |
Concentration | lot specific |
Purification | Affinity chromatography on Protein A |
Conjugation | Unconjugated |
Storage Condition | Store the antibody undiluted at 2 - 8 °C up to one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing. Should this product contain a precipitate we recommend microcentrifugation before use. |
Database Link | |
Background | Mycobacterium tuberculosis is the most common cause of tuberculosis. Primary infection begins with inhalation of 1 to 10 aerosolised bacilli. The pathogenicity of the organism is determined by its ability to escape host immune responses as well as eliciting delayed hypersensitivity. Alveolar macrophages engulf the invading cells but are unable to mount an effective defense. Several virulence factors are responsible for this apparent failure; most notably in the mycobacterial cell wall are the cord factor, lipoarabinomannan, and the 65 kd heat shock protein or HSP65. The emergence of new strains of resistant Mycobacterium tuberculosis has created new interest in clinical diagnosis. Studies have shown immunohistochemical techniques to be superior to conventional special stains. Thus the demonstration of mycobacterial antigens are not only useful in establishing mycobacterial aetiology, but can also be used as an alternative method to the conventional Ziehl-Neelsen method. |
Synonyms | M. tuberculosis, TB |
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