TGF beta 1 (TGFB1) Mouse Monoclonal Antibody [Clone ID: GE 4.90]

Specifications

Product Data
Clone Name	GE 4.90
Applications	ELISA, WB
Recommend Dilution	ELISA: 1/10000. Western Bloting: 1/500 - 1/2000.
Reactivity	Human
Host	Mouse
Clonality	Monoclonal
Immunogen	Purified recombinant fragment of TGF beta1 expressed in E. Coli.
Specificity	Recognizes TGF beta-1
Formulation	State: Ascites State: Ascitic fluid Preservative: 0.03% Sodium Azide
Conjugation	Unconjugated
Storage Condition	Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing.
Gene Name	transforming growth factor beta 1
Database Link	Entrez Gene 7040 Human UniProt ID P01137
Background	TGF beta (transforming growth factor beta), with 390-amino acid protein (about 43 kDa), is a multifunctional peptide that controls proliferation, differentiation, and other functions in many cell types. In mammals, three isoforms of TGFbeta, that is, beta1, beta2,and beta3,are known. TGF beta is one of numerous inhibitory factors produced by cancer cells that regulate antitumor immunity. TGF beta1 takes part in the local response in the course of primary lung cancer and TGFbeta1 is thought to be implicated in breast cancer progression.TGFbeta1 also plays a critical role in the downregulation of microglial responses minimizing brain inflammation and thus avoiding exacerbation of brain damage.
Synonyms	TGFB, Transforming growth factor beta-1, TGF-beta-1
Reference Data

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