SRC3 (NCOA3) Mouse Monoclonal Antibody [Clone ID: 2C11B12]

Specifications

Product Data
Clone Name	2C11B12
Applications	WB
Recommend Dilution	ELISA: 1/10000. Western Blot: 1/500 - 1/2000.
Reactivity	Human
Host	Mouse
Clonality	Monoclonal
Immunogen	Purified recombinant fragment of NCOA3 (aa1-200) expressed in E. Coli.
Specificity	Recognize nuclear receptor coactivator 3 (NCOA3)
Formulation	State: Ascites State: Ascitic fluid containing 0.03% Sodium Azide.
Conjugation	Unconjugated
Storage Condition	Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing.
Gene Name	nuclear receptor coactivator 3
Database Link	Entrez Gene 8202 Human UniProt ID Q9Y6Q9
Background	The protein encoded by this gene is a nuclear receptor coactivator that interacts with nuclear hormone receptors to enhance their transcriptional activator functions. The encoded protein has histone acetyltransferase activity and recruits p300/CBP-associated factor and CREB binding protein as part of a multisubunit coactivation complex. This protein is initially found in the cytoplasm but is translocated into the nucleus upon phosphorylation. Two transcript variants encoding different isoforms have been found for this gene. In addition, a polymorphic repeat region is found in the C-terminus of the encoded protein.
Synonyms	NCoA-3, Nuclear receptor coactivator 3, SRC-3, Steroid receptor coactivator protein 3, TRAM-1, TRAM1, RAC-3, RAC3, AIB-1, AIB1, pCIP, ACTR, BHLHE42
Reference Data

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