OLIG2 Mouse Monoclonal Antibody [Clone ID: 1G11]

Specifications

Product Data
Clone Name	1G11
Applications	ELISA, IF, IHC, WB
Recommend Dilution	ELISA: 1/10000. Western Blot: 1/500 - 1/2000. Immunofluorescence: 1/200 - 1/1000. Immunohistochemistry on Paraffin Sections: 1/200 - 1/1000.
Reactivity	Human
Host	Mouse
Clonality	Monoclonal
Immunogen	Purified recombinant fragment of Human OLIG2 expressed in E. Coli.
Specificity	Recognizes OLIG2
Formulation	State: Ascites State: Ascitic fluid containing 0.03% Sodium Azide.
Conjugation	Unconjugated
Storage Condition	Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing.
Predicted Protein Size	32 kDa
Gene Name	oligodendrocyte lineage transcription factor 2
Database Link	Entrez Gene 10215 Human UniProt ID Q13516
Background	This gene encodes a basic helix-loop-helix transcription factor which is expressed in oligodendroglial tumors of the brain. The protein is an essential regulator of ventral neuroectodermal progenitor cell fate. The gene is involved in a chromosomal translocation t(14;21)(q11.2;q22) associated with T-cell acute lymphoblastic leukemia. Its chromosomal location is within a region of chromosome 21 which has been suggested to play a role in learning deficits associated with Down syndrome. Tissue specificity: Expressed in the brain, in oligodendrocytes. Strongly expressed in oligodendrogliomas, while expression is weak to moderate in astrocytomas. Expression in glioblastomas highly variable.
Synonyms	OLIG2, BHLHB1, PRKCBP2, RACK17, Oligodendrocyte transcription factor 2, Oligo2, bHLHB1
Reference Data

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