MTHFR Mouse Monoclonal Antibody [Clone ID: 5D3]

Specifications

Product Data
Clone Name	5D3
Applications	ELISA, IHC, WB
Recommend Dilution	Western Blot: 1/500 - 1/2000. Immunohistochemistry on paraffin sections: 1/200 - 1/1000. ELISA: 1/10000.
Reactivity	Human, Rat
Host	Mouse
Clonality	Monoclonal
Immunogen	Purified recombinant fragment of human MTHFR expressed in E. Coli.
Specificity	This antibody reacts to MTHFR.
Formulation	State: Ascites State: Ascitic fluid containing 0.03% sodium azide.
Conjugation	Unconjugated
Storage Condition	Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing.
Gene Name	methylenetetrahydrofolate reductase (NAD(P)H)
Database Link	Entrez Gene 4524 Human UniProt ID P42898
Background	The protein encoded by this gene catalyzes the conversion of 5,10-methylenetetrahydrofolate to 5-methyltetrahydrofolate, a co-substrate for homocysteine remethylation to methionine. Genetic variation in this gene influences susceptibility to occlusive vascular disease, neural tube defects, colon cancer and acute leukemia, and mutations in this gene are associated with methylenetetrahydrofolate reductase deficiency.
Synonyms	Methylenetetrahydrofolate reductase
Reference Data

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