LIMS1 Mouse Monoclonal Antibody [Clone ID: 5G7]
CAT#: AM06652SU-N
LIMS1 mouse monoclonal antibody, clone 5G7, Ascites
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CNY 5,775.00
货期*
5周
规格
Specifications
Product Data | |
Clone Name | 5G7 |
Applications | ELISA, FC, IF, WB |
Recommend Dilution | Western Blot: 1/500 - 1/2000. Immunofluorescence: 1/200 - 1/1000. Flow cytometry: 1/200 - 1/400. ELISA: 1/10000. |
Reactivity | Human |
Host | Mouse |
Clonality | Monoclonal |
Immunogen | Purified recombinant fragment of human PINCH expressed in E. Coli. |
Specificity | This antibody reacts to PINCH. |
Formulation | State: Ascites State: Ascitic fluid containing 0.03% sodium azide. |
Conjugation | Unconjugated |
Storage Condition | Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. |
Predicted Protein Size | 37 kDa |
Gene Name | LIM zinc finger domain containing 1 |
Database Link | |
Background | The protein encoded by this gene is an adaptor protein which contains five LIM domains, or double zinc fingers. The protein is likely involved in integrin signaling through its LIM domain-mediated interaction with integrin-linked kinase, found in focal adhesion plaques. It is also thought to act as a bridge linking integrin-linked kinase to NCK adaptor protein 2, which is involved in growth factor receptor kinase signaling pathways. Its localization to the periphery of spreading cells also suggests that this protein may play a role in integrin-mediated cell adhesion or spreading. Several transcript variants encoding different isoforms have been found for this gene. |
Synonyms | LIMS-1, PINCH, PINCH1, Particularly interesting new Cys-His protein 1, PINCH-1, Renal carcinoma antigen NY-REN-48 |
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