IRAK4 Mouse Monoclonal Antibody [Clone ID: 2H9]

Specifications

Product Data
Clone Name	2H9
Applications	ELISA, FC, IHC, WB
Recommend Dilution	Western Blot: 1/500 - 1/2000. Immunohistochemistry on paraffin sections: 1/200 - 1/1000. Flow cytometry: 1/200 - 1/400. ELISA: 1/10000.
Reactivity	Human, Monkey, Mouse
Host	Mouse
Clonality	Monoclonal
Immunogen	Purified recombinant fragment of human IRAK4 expressed in E. Coli.
Specificity	This antibody reacts to IRAK4.
Formulation	State: Ascites State: Ascitic fluid containing 0.03% sodium azide.
Conjugation	Unconjugated
Storage Condition	Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing.
Predicted Protein Size	52 kDa
Gene Name	interleukin 1 receptor associated kinase 4
Database Link	Entrez Gene 51135 Human UniProt ID Q9NWZ3
Background	This gene encodes a kinase that activates NF-kappaB in both the Toll-like receptor (TLR) and T-cell receptor (TCR) signaling pathways. The protein is essential for most innate immune responses. Mutations in this gene result in IRAK4 deficiency and recurrent invasive pneumococcal disease. Multiple transcript variants encoding different isoforms have been found for this gene.
Synonyms	IRAK-4, NY-REN-64
Reference Data

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