SRC Mouse Monoclonal Antibody [Clone ID: 1F11]

Specifications

Product Data
Clone Name	1F11
Applications	ELISA, FC, IHC, WB
Recommend Dilution	ELISA: 1/10000.  Flow Cytometry: 1/200-1/400.  Western Blot: 1/500-1/2000. Immunohistochemistry on Paraffin Sections: 1/200-1/1000.
Reactivity	Human
Host	Mouse
Clonality	Monoclonal
Immunogen	Purified recombinant fragment of Human SRC expressed in E. Coli.
Specificity	This antibody recognizes Human SRC. Other species not tested.
Formulation	State: Ascites State: Liquid Ascitic fluid Preservative: 0.03% Sodium Azide
Conjugation	Unconjugated
Storage Condition	Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing.
Predicted Protein Size	60 kDa
Gene Name	SRC proto-oncogene, non-receptor tyrosine kinase
Database Link	Entrez Gene 6714 Human UniProt ID P12931
Background	This gene is highly similar to the v-src gene of Rous sarcoma virus. This proto-oncogene may play a role in the regulation of embryonic development and cell growth. The protein encoded by this gene is a tyrosine-protein kinase whose activity can be inhibited by phosphorylation by c-SRC kinase. Mutations in this gene could be involved in the malignant progression of colon cancer. Two transcript variants encoding the same protein have been found for this gene.
Synonyms	c-Src, pp60c-src
Reference Data

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