Cd24a Rat Monoclonal Antibody [Clone ID: 91]

Specifications

Product Data
Clone Name	91
Applications	FC
Recommend Dilution	Flow Cytometry: < / = 4 µg/10e6 cells. (Ref.8)
Reactivity	Mouse
Host	Rat
Clonality	Monoclonal
Specificity	This antibody is specific to Heat Stable Antigen HSA (Mr 35-45 kDa).
Formulation	PBS containing 0.09% Sodium Azide as preservative. Label: FITC State: Liquid purified Ig fraction. Label: Fluorescein Isothiocyanate Isomer 1
Concentration	lot specific
Conjugation	FITC
Storage Condition	Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. This product is photosensitive and should be protected from light. Avoid repeated freezing and thawing.
Gene Name	CD24a antigen
Database Link	Entrez Gene 12484 Mouse UniProt ID P24807
Background	CD24, also known as heat stable antigen, is a phosphatidylinositol-linked cell surface glycoprotein that is expressed at all stages of B cell development and on most thymocytes. (Ref.1-3) The absence of expression from mature T cells is closely associated with their maturation from CD4+CD8+CD24+ thymocytes to either CD4+CD8-CD24- or CD4-CD8+CD24- T cells. CD24 is also present on mouse granulocytes, monocytes, Langerhans cells and erythrocytes. (Ref.4-6) Its ligand is P-selectin (CD62P). (Ref.7) CD24 may play a role in regulation of B cell proliferation and differentiation, and it has been proposed that heat stable antigen promotes homotypic adhesion between B lymphocytes. (Ref.1-3). The monoclonal antibody 91 can be used to inhibit B-cell differentiation. (Ref.8)
Synonyms	X62 heat stable antigen, HSA
Reference Data

*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.