Cd24a Rat Monoclonal Antibody [Clone ID: 91]

Specifications

Product Data
Clone Name	91
Applications	FC, IHC, IP
Recommend Dilution	Flow Cytometry. (Ref.8) Immunohistochemistry on Frozen Sections. (Ref.8) Immunoprecipitation. (Ref.8) Clone 91 can be used to inhibit B-cell differentiation. (Ref.8)
Reactivity	Mouse
Host	Rat
Clonality	Monoclonal
Specificity	This antibody is specific to Heat Stable Antigen HSA (Mr 35-45 kDa).
Formulation	100 mM Borate Buffered Saline, pH 8.2. No preservatives or amine-containing buffer salts added. State: Purified State: Liquid purified Ig fraction.
Concentration	lot specific
Conjugation	Unconjugated
Storage Condition	Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing.
Gene Name	CD24a antigen
Database Link	Entrez Gene 12484 Mouse UniProt ID P24807
Background	CD24, also known as heat stable antigen, is a phosphatidylinositol-linked cell surface glycoprotein that is expressed at all stages of B cell development and on most thymocytes. (Ref.1-3) The absence of expression from mature T cells is closely associated with their maturation from CD4+CD8+CD24+ thymocytes to either CD4+CD8-CD24- or CD4-CD8+CD24- T cells. CD24 is also present on mouse granulocytes, monocytes, Langerhans cells and erythrocytes. (Ref.4-6) Its ligand is P-selectin (CD62P). (Ref.7) CD24 may play a role in regulation of B cell proliferation and differentiation, and it has been proposed that heat stable antigen promotes homotypic adhesion between B lymphocytes. (Ref.1-3)
Synonyms	X62 heat stable antigen, HSA
Reference Data

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