Thy1 Rat Monoclonal Antibody [Clone ID: G7]

Specifications

Product Data
Clone Name	G7
Applications	FC
Recommend Dilution	Flow Cytometry: ≤ 1 µg/106 cells. (Ref.1, 6-8)
Reactivity	Mouse
Host	Rat
Clonality	Monoclonal
Immunogen	Mouse T cell hybridoma C6/G8
Specificity	This antibody recognises Thy-1.1 and Thy-1.2 alloantigens (Thy-1 epitope region A), Mr 28-32 kDa.
Formulation	PBS containing 0.09% Sodium Azide as preservative. Label: FITC State: Liquid purified Ig fraction. Label: Fluorescein Isothiocyanate Isomer 1
Concentration	lot specific
Conjugation	FITC
Storage Condition	Store the antibody undiluted at 2-8°C. This product is photosensitive and should be protected from light. Avoid repeated freezing and thawing.
Gene Name	thymus cell antigen 1, theta
Database Link	Entrez Gene 21838 Mouse UniProt ID P01831
Background	CD90/Thy-1, a GPI-anchored molecule and one of the smallest members of the immunoglobulin superfamily of cell surface receptors, consists of a single V-set domain. (Ref.1-4) It is expressed on thymocytes, peripheral T lymphocytes, some intraepithelial T lymphocytes and neurons of all mouse strains. (Ref.1,2) MAb G7 stimulates T-cell proliferation and IL-2 secretion, via signalling through the T-cell receptor/CD3 complex. (Ref.1,5-7). It has also been reported to promote apoptosis of thymocytes and CTL clones (Ref.4,7) and to mediate adhesion of thymocytes to thymic stroma. (Ref.8)
Synonyms	Thy-1, THY1, CDw90
Reference Data

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